PhD studentship: Comprehensive taxonomy, pangenomics and metabolic modelling of Streptomyces.
University of Strathclyde
Scotland, UK
Funded PhD Project (European/UK Students Only)
This project aims to: (i) improve genome mining for novel antimicrobial (and other) targets by decoding the evolutionary history of the taxonomically-complex Streptomyces genus and its secondary metabolite (antibiotic) synthetic clusters using whole- and pan-genome analysis; and (ii) identify useful traits for synthetic biology and industrial processes using pangenome analyses and genome-scale metabolic models. These models will allow quantitative assessment of predicted phenotypic differences, and for speculative “what if?” (knockout/substrate variation/etc.) experiments in silico.
Qualifications
The project would suit a candidate with a 2.1 degree or better in Microbiology, Biotechnology, Biochemistry, and a strong interest in computational biology and bioinformatics. (European/UK students only, due to funding constraints).
Job Information
Start Date: October 01, 2020
Duration: NA
Status: Open
Contact Information
University of Strathclyde
Strathclyde Institute for Pharmacy and Biomedical Sciences (SIPBS)
Leighton Pritchard
leighton.pritchard@strath.ac.ukhttps://www.findaphd.com/phds/project/comprehensive-taxonomy-pangenomics-and-metabolic-modelling-of-streptomyces/?p122236 How To Apply:
Please apply through the FindAPhD page: https://www.findaphd.com/phds/project/comprehensive-taxonomy-pangenomics-and-metabolic-modelling-of-streptomyces/?p122236